Atypical juvenile hereditary hemochromatosis onset with positive pancreatic islet autoantibodies diabetes caused by novel mutations in HAMP and overall clinical management

ConclusionIt was first reported that positive pancreatic islet autoantibodies diabetes onset of JHH resulted from loss ‐of‐function mutations ofHAMP, of which the atypical JHH should be differentially diagnosed with type 1 diabetes at the onset. Early administration of phlebotomy and vital organs protection and surveillance might be important for the treatment of atypical JHH.

Source: Molecular Genetics & Genomic Medicine - October 4, 2020 Category: Genetics & Stem Cells Authors: Hui ‐Xuan Wu, Jun‐Ying Liu, De‐Wen Yan, Long Li, Xiang‐Hua Zhuang, Hai‐Yan Li, Zhi‐Guang Zhou, Hou‐De Zhou Tags: ORIGINAL ARTICLE Source Type: research