Incidence of venous thromboembolism in coronavirus disease 2019: An experience from a single large academic center

Publication date: Available online 5 October 2020Source: Journal of Vascular Surgery: Venous and Lymphatic DisordersAuthor(s): Parth Rali, Oisin O'Corragain, Lawrence Oresanya, Daohai Yu, Omar Sheriff, Robert Weiss, Catherine Myers, Parag Desai, Nadia Ali, Anthony Stack, Michael Bromberg, Andrea L. Lubitz, Joseph Panaro, Riyaz Bashir, Vladimir Lakhter, Roberto Caricchio, Rohit Gupta, Chandra Dass, Kumaran Maruti, Xiaoning Lu
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - Category: Surgery Source Type: research

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AbstractTransesophageal echocardiography (TEE) is the gold standard for assessing left atrial appendage (LAA) mechanic and thrombosis (LAAT); however, TEE is a high-risk procedure for viral transmission during coronavirus disease 2019 (COVID-19) pandemic. We investigated whether deformation indices of left atrium (LA) at transthoracic echocardiography (TTE) correlate with those of LAA assessed by TEE in nonvalvular atrial fibrillation (NVAF) patients undergoing electrical cardioversion (ECV). Consecutive patients with NVAF of  ≥ 48 h or unknown duration, who underwent TEE and TTE at our Institution be...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research
Since late 2020, a rare prothrombotic thrombocytopenic condition has been observed to arise within 5 to 30  days after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1]. This condition – called “Vaccine Induced Immune Thrombotic Thrombocytopenia” (VITT) – has many similarities to an atypical variant of heparin-induced thrombocytopenia, including unusual sites for VTE, in addition to positive platelet-activating antibodies against platelet factor 4 (PF4) [2]. Prior to SARS-CoV-2, “spontaneous HIT” was described in the absence of proximate exposure to heparin [3].
Source: Thrombosis Research - Category: Hematology Authors: Tags: Letter to the Editors-in-Chief Source Type: research
Recently, heparin-induced thrombocytopenia (HIT) after vaccination with the vaccines manufactured by AstraZeneca and Pfizer –BioNTech has been published in the New England Journal of Medicine. These reports state ...
Source: Thrombosis Journal - Category: Hematology Authors: Tags: Letter to the Editor Source Type: research
In the letter to the Editor by Zuin et al. [1], the authors raise several interesting points concerning the uncertainties linking coronavirus disease 2019 (COVID-19) to thrombosis, especially in the settings of acute coronary syndromes (ACS).
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
Int J Lab Hematol. 2021 Sep 14. doi: 10.1111/ijlh.13705. Online ahead of print.ABSTRACTIn December 2019, several cases of pneumonia of unknown aetiology were reported in Wuhan, China. The causative Coronavirus was subsequently isolated and named the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) and the disease, Coronavirus disease-2019 (COVID-19).1 COVID-19 related coagulopathy is a poor prognostic feature and reflects an underlying pathological process termed immunothrombosis.2 This process differs from infection-related disseminated intravascular coagulation (DIC) as it manifests primarily with thrombosis ...
Source: International Journal of Laboratory Hematology - Category: Hematology Authors: Source Type: research
CONCLUSIONS: Among patients hospitalized for COVID-19, VT is a relatively common finding, with higher prevalence rates in ICU patients. VT occurs mostly in the distal regions of the lower limb and is asymptomatic in most cases. Older age, obesity and higher D-dimer values on admission increased the odds of VT, while female sex was protective against the odds of VT.PMID:34520137 | DOI:10.23736/S0021-9509.21.12022-1
Source: The Journal of Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
Int J Lab Hematol. 2021 Sep 14. doi: 10.1111/ijlh.13705. Online ahead of print.ABSTRACTIn December 2019, several cases of pneumonia of unknown aetiology were reported in Wuhan, China. The causative Coronavirus was subsequently isolated and named the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) and the disease, Coronavirus disease-2019 (COVID-19).1 COVID-19 related coagulopathy is a poor prognostic feature and reflects an underlying pathological process termed immunothrombosis.2 This process differs from infection-related disseminated intravascular coagulation (DIC) as it manifests primarily with thrombosis ...
Source: International Journal of Laboratory Hematology - Category: Hematology Authors: Source Type: research
CONCLUSIONS: Among patients hospitalized for COVID-19, VT is a relatively common finding, with higher prevalence rates in ICU patients. VT occurs mostly in the distal regions of the lower limb and is asymptomatic in most cases. Older age, obesity and higher D-dimer values on admission increased the odds of VT, while female sex was protective against the odds of VT.PMID:34520137 | DOI:10.23736/S0021-9509.21.12022-1
Source: The Journal of Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
CONCLUSIONS: Our study warns the clinicians to maintain a high index of suspicion for thrombosis in patients diagnosed with SARS-CoV-2 infection manifesting gastrointestinal symptoms. An appropriate diagnostic work-up could allow to obtain an early diagnosis and consequently improve the clinical outcome of patients.PMID:34511494 | DOI:10.3233/CH-211256
Source: Clinical Hemorheology and Microcirculation - Category: Hematology Authors: Source Type: research
CONCLUSIONS: In conclusion, we found that higher total cholesterol and ApoB levels might increase the risk of COVID-19 infection.PMID:34496635 | DOI:10.1161/ATVBAHA.121.316324
Source: Arteriosclerosis, Thrombosis and Vascular Biology - Category: Cardiology Authors: Source Type: research
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