BRAFV600E overrides NOTCH signaling in thyroid cancer.

CONCLUSIONS: The interaction between the BRAF and NOTCH pathways demonstrates that BRAFV600E mutation might bypass NOTCH and exert a strong positive effect on NOTCH downstream targets in thyroid carcinoma.
PMID: 33012268 [PubMed - as supplied by publisher]

Source: Thyroid : official journal of the American Thyroid Association - October 6, 2020 Category: Endocrinology Tags: Thyroid Source Type: research