Intraoperative changes in the H-reflex pathway during Deep Brain Stimulation surgery for Parkinson ’s Disease: a potential biomarker for optimal electrode placement

Deep Brain Stimulation (DBS) targeting the subthalamic nucleus (STN) and globus pallidus interna (GPi) is an effective treatment for cardinal motor symptoms and motor complications in Parkinson ’s Disease (PD). However, malpositioned DBS electrodes can result in suboptimal therapeutic response.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research