Looking for Amyloid in All the Right Places

Systemic amyloidosis remains a challenging diagnosis, but over the past several years, due to an increase in awareness and therapeutic advances, more cases are being identified. There are numerous types of systemic amyloidosis, defined by the protein that comprises the amyloid fibrils, with at least 13 types known to potentially involve the heart (Table1-3;). The two most common forms are transthyretin-associated (ATTR) and immunoglobulin light chain-associated amyloidosis (AL). These disorders contribute to the vast majority of cardiac amyloid diagnoses.

Source: Journal of Cardiac Failure - October 4, 2020 Category: Cardiology Authors: Emily B. Martin, Jonathan S. Wall Source Type: research