Prostatic Artery Embolization in Refractory Hematuria of Prostatic Origin.

Hematuria of prostatic origin has multiple etiologies including benign prostatic hyperplasia (BPH), iatrogenic urological trauma, prostate cancer, and radiation therapy. Hematuria secondary to benign prostatic hyperplasia (BPH) can occur because of the increased vascularity of the primary gland, itself, or because of the vascular re-growth following a transurethral resection of the prostate. Prostatic hematuria usually resolves with conservative measures; however, refractory hematuria of prostatic origin (RHPO) may require hospitalization with treatment with blood transfusions, repeated indwelling urinary catheterization, and continuous bladder irrigation.
Source: Techniques in Vascular and Interventional Radiology - Category: Radiology Authors: Source Type: research

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Authors: Murphy N, Shah P, Shih A, Khalili H, Liew A, Zhu X, Lee A Abstract Single-cell sequencing (SCS) is a powerful new tool that applies Next Generation Sequencing at the cellular level. SCS has revolutionized our understanding of tumor heterogeneity and the tumor microenvironment, immune infiltration, cancer stem cells (CSCs), circulating tumor cells (CTCs), and clonal evolution. The following chapter highlights the current literature on SCS in genitourinary (GU) malignancies and discusses future applications of SCS technology. The renal cell carcinoma (RCC) section highlights the use of SCS in characterizing ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Abstract Bladder neck stenosis (BNS) after simple prostatectomy and vesicourethral anastomosis stenosis (VUAS) after radical prostatectomy for prostate cancer are common sequelae. However, the two entities differ in their pathology, anatomy and their surgical results. VUAS has an incidence of 0.2-28%. Commonly, VUAS occurs within the first 2 years after surgery. Initial therapy should be performed endourologically: dilatation, (laser) incision or resection. After three unsuccessful treatment attempts, open reconstruction should be considered. Different surgical approaches (abdominal, perineal, abdominoperinea...
Source: Der Urologe. Ausg. A - Category: Urology & Nephrology Authors: Tags: Urologe A Source Type: research
Purpose of review To summarize recent publications on the topic of laser in urology and explore new developments which may impact the future role of lasers in surgery. Recent findings Ho: Yttrium-aluminium garnet (YAG) laser with Moses technology allows less retropulsion during a lithotripsy, yet its efficacy needs to be tested in clinical trials. Data on the efficacy of this device for benign prostatic obstruction treatment is also pending. A new promising generation of laser systems – thulium-fiber (Tm-fiber) lasers – has been introduced. Tm-fiber has already been shown to be effective and well tolerated...
Source: Current Opinion in Urology - Category: Urology & Nephrology Tags: BEST OF 2019: Edited by Johannes W. Vieweg and Shahrokh F. Shariat Source Type: research
Publication date: Available online 23 November 2019Source: Journal of Vascular and Interventional RadiologyAuthor(s): Raj Ayyagari, Taylor Powell, Lawrence Staib, Julius Chapiro, Anusha Raja, Shivank Bhatia, Toby Chai, Steven Schoenberger, Ralph DevitoAbstractPurposeTo report medium-term outcomes of prostatic artery embolization (PAE) using 100–300-μm trisacryl gelatin microspheres to treat lower urinary tract symptoms (LUTS) from benign prostatic hyperplasia (BPH) and to evaluate how cone-beam computed tomography-measured prostate gland volume (PGV), median lobe enlargement (MLE), age, and Charlson Comorbidity In...
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research
The prostates of older mice contain more luminal progenitor cells — cells capable of generating new prostate tissue — than the prostates of younger mice, UCLA researchers have discovered.The observation,published in  Cell Reports, helps explain why, as people age, the prostate tends to grow, leading to an increased risk for prostate cancer and other conditions.“Understanding what’s causing the prostate to grow with age helps us to consider strategies to prevent the expansion of these cells and possibly reduce a person’s risk for prostate growth or disease,” said Andrew Goldstein, me...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
This report may help to increase awareness of BOO as a late complication of pelvic reconstruction.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
AbstractPurpose of ReviewTo summarize recent investigation into associations between the genitourinary microbiota and prostatic disease.Recent FindingsThe genitourinary tract is not sterile. There are microbial communities (microbiota) in each niche of the genitourinary tract including the bladder, prostate, and urethra, which have been the subject of increasing scientific interest. Investigators have utilized several unique methods to study them, resulting in a highly heterogeneous body of literature. To characterize these genitourinary microbiota, diverse clinical specimens have been analyzed, including urine obtained by...
Source: Current Urology Reports - Category: Urology & Nephrology Source Type: research
This study is an important step forward in highlighting C1q as a new prognostic candidate biomarker for a range of carcinomas. Methods Oncomine Database Analysis The expression levels of C1QA, C1QB, and C1QC genes in various carcinomas were analyzed using Oncomine (www.oncomine.org), a cancer microarray database and web-based data mining platform from genome-wide expression analyses (22, 23). We compared the differences in mRNA level between normal tissue and carcinoma. The mRNA expression levels in neoplastic tissues compared to the healthy tissues were obtained as the parameters of p-value 2, and gene ranking in the t...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
AbstractPurpose of ReviewTreatment of lower urinary tract symptoms attributed to benign prostatic hyperplasia (BPH) can present a surgical dilemma for elderly patients, especially in those with multiple comorbidities. The purpose of this paper is to review recent publications on this topic and highlight the benefits of holmium laser enucleation of the prostate (HoLEP) in such patients.Recent FindingsHoLEP is a safe and effective treatment option for patients with BPH of any age with any prostate size. It is superior to many other BPH treatment options. It can be safely completed in those on anticoagulants, in the re-treatm...
Source: Current Geriatrics Reports - Category: Geriatrics Source Type: research
AbstractIntroductionSilodosin determines smooth muscle relaxation in bladder and prostate tissues, increases bladder blood flow in conditions of chronic bladder ischemia and regulates the activity of transcriptional factors responsible for stromal growth and prostate hyperplasia. Phase III trials have already demonstrated the efficacy and safety of silodosin in the treatment of patients bothered by lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH).ObjectiveWe aimed to describe the rationality for the use of silodosin and to summarize the current literature on the use of Silodosin for the t...
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
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