Critical repolarization gradients determine the induction of reentry-based Torsade de Pointes arrhythmia in models of long QT syndrome.

Torsade de Pointes arrhythmia is a potentially lethal polymorphic ventricular tachyarrhythmia (pVT) in the setting of long QT syndrome. Arrhythmia susceptibility is influenced by risk factors modifying repolarization.

Source: Heart Rhythm - October 3, 2020 Category: Cardiology Authors: Mathilde R. Rivaud, Jason D. Bayer, Matthijs Cluitmans, Jeanne van der Waal, Laura R. Bear, Bastiaan J. Boukens, Charly Belterman, Lisa Gottlieb, Fanny Vaillant, Emma Abell, Remi Dubois, Veronique M.F. Meijborg, Ruben Coronel Source Type: research