Women diagnosed with Ductal Carcinoma In Situ (DCIS) and healthcare providers ’ views on active surveillance for DCIS. Results from focus groups and in-depth interviews

Background: Low-risk ductal carcinoma in situ (DCIS) lesions carry a risk of progressing to invasive breast cancer (iBC). Therefore, women with DCIS undergo surgery ±radiotherapy which will yield many of them no/limited survival benefit whilst the associated side-effects can significantly impact their quality of life (QoL). The safety of active surveillance (AS) via yearly mammographic screening for low-risk DCIS is now being investigated. AS minimizes the phy sical burden associated with the standard treatments, but foregoing treatment could cause increased worry about progression of the DCIS lesion to iBC.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: POSTERS A: Local Regional Treatment – Surgery Source Type: research

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This study investigated the clinical audit history for a cohort of 39 participants in the BreastScreen Reader Assessment Strategy who have read for BreastScreen New South Wales in the period between 2010 and 2018, inclusively. Based on the year in which each radiologist completed his or her first test set, data of multiple clinical audit metrics from two calendar years before test-set reading were compared against similar data from three different periods after test-set completion. The same process was repeated after dividing radiologists into two subgroups based on their median screen-reading volume (3,688), to test if ex...
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSION: For detecting underestimated DCIS, CESM was superior to mammography and breast US, and comparable to breast MRI.PMID:34776365 | DOI:10.1016/j.clbc.2021.10.004
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research
Women undergoing breast MRI for evaluation of ductal carcinoma in situ experienc...Read more on AuntMinnie.comRelated Reading: Contrast-enhanced mammography can predict underestimated DCIS Prediction models can reduce false positives in breast MRI screening DCIS shows as nonmass enhancement on breast MRI Health practitioners overestimate likelihood of disease, study says Women with DCIS have 3x the risk of breast cancer death
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
CONCLUSIONS: There is low-/very low-certainty evidence to support the hypothesis that breast density change following endocrine therapy is a prognostic biomarker for treatment or prevention. Studies suggested a potentially large effect size with tamoxifen, but the evidence was limited. There was less evidence that breast density change following tamoxifen preventive therapy is a predictive biomarker than prognostic biomarker. Evidence for breast density change as a prognostic treatment biomarker was stronger for tamoxifen than aromatase inhibitors. There were no studies reporting mammographic density change following endoc...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Source Type: research
Dr. Laura Esserman answers the door of her bright yellow Victorian home in San Francisco’s Ashbury neighborhood with a phone at her ear. She’s wrapping up one of several meetings that day with her research team at University of California, San Francisco, where she heads the Carol Franc Buck Breast Care Center. She motions me in and reseats herself at a makeshift home office desk in her living room, sandwiched between a grand piano and set of enormous windows overlooking her front yard’s flower garden. It’s her remote base of operations when she’s not seeing patients or operating at the hospita...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: news
CONCLUSION: In DCIS patients, the rate of second breast cancers was 7.5%. Breast conservation, involved margins after lumpectomy and shortened hormonal therapy were associated with second cancers. Patients with involved margins after lumpectomy have the highest cancer detection rate and minimal unnecessary biopsies and follow-ups. Hence, ipsilateral breast ultrasound surveillance could be personalized for this high-risk group with mammographically dense breasts.PMID:34544658 | DOI:10.1016/j.clbc.2021.08.006
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research
The three risk assessment tools now in use fall far short. Using the latest deep learning techniques, investigators are developing more personalized ways to locate women at high risk.John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article.The promise of personalized medicine will eventually allow clinicians to offer individual patients more precise advice on prevention, early detection and treatment. Of course, the operative word iseventually.A closer examination of the screening tools available to detect breast c...
Source: Life as a Healthcare CIO - Category: Information Technology Source Type: blogs
The incidence of ductal carcinoma in situ (DCIS) is increasing due to more widespread mammographic screening. DCIS, the earliest form of breast cancer, is non-invasive at the time of detection. If DCIS tissues...
Source: BMC Research Notes - Category: Research Authors: Tags: Data note Source Type: research
CONCLUSION: RT significantly reduced all and invasive IBR for good-risk DCIS with durable results at 15 years. These results are not an absolute indication for RT but rather should inform shared patient-physician treatment decisions about ipsilateral breast risk reduction in the long term following lumpectomy.PMID:34406870 | DOI:10.1200/JCO.21.01083
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Source Type: research
Clin Breast Cancer. 2021 Jul 13:S1526-8209(21)00180-4. doi: 10.1016/j.clbc.2021.07.003. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate factors contributing to positive surgical margins associated with reflector guidance for patients undergoing breast conserving therapy for malignancy.MATERIALS AND METHODS: A retrospective IRB-approved review of our institutional database was performed for malignant breast lesions preoperatively localized from January 1, 2018 to December 31, 2020. The following data was recorded using electronic medical records: lesion type and grade, lesion location, reflector and wire placement moda...
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research
More News: Breast Cancer | Breast Carcinoma | Cancer | Cancer & Oncology | Carcinoma | Carcinoma in Situ | DCIS (Ductal Carcinoma in Situ) | Ductal Carcinoma | Mammography | Women