Emotional dysregulation and uncertainty intolerance as transdiagnostic mediators of anxiety in adults with autism spectrum disorders and intellectual disability

Publication date: November 2020Source: Research in Developmental Disabilities, Volume 106Author(s): Gema P. Sáez-Suanes, Domingo García-Villamisar, Araceli del Pozo Armentia, John Dattilo
Source: Research in Developmental Disabilities - Category: Disability Source Type: research

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Families of children with neurodevelopmental disorders are especially vulnerable during the COVID-19 pandemic. Physical distancing requirements and closure of schools and services in the context of the COVID-19 pandemic are likely challenging to everyone but may be particularly impactful for families with children with neurodevelopmental disorders ([NDDs], eg, intellectual disability, attention-deficit/hyperactivity disorder [ADHD], autism spectrum disorder [ASD]). Although a small number of children may experience less stress or anxiety due to reduced social and academic expectations,1 for many children with NDDs, and par...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: Letter to the Editor Source Type: research
Fragile X syndrome (FXS) is the most common identifiable cause of inherited intellectual disability and autism spectrum conditions, and is associated with a range of physical, cognitive and behavioural characteristics. Alongside intellectual disability, heightened rates of autism spectrum disorder, anxiety disorders, attention-deficit-hyperactivity disorder, self-injury and aggression are reported. Timely identification of FXS as well as assessments of common co-morbid psychological conditions and underlying health problems are essential to ensure individuals with FXS receive appropriate support.
Source: Paediatrics and Child Health - Category: Pediatrics Authors: Tags: Personal practice Source Type: research
This study provides further evidence that maternal PCOS and/or anovulatory infertility, independently and jointly with maternal obesity, perinatal problems, gestational diabetes and cesarean delivery, implies a broad range of adverse effects on offspring neurodevelopment. These findings may potentially help in counseling and managing pregnancies.STUDY FUNDING/COMPETING INTEREST(S)This study was supported by the joint research funding of Shandong University and Karolinska Institute (SDU-KI-2019-08 to X.C and C.L.), THL Finnish Institute for Health and Welfare: Drug and pregnancy project [M.G.], the Swedish Research Council ...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research
FMR1 has a dynamic trinucleotide CGG repeat element in the promotor region, and when the CGG repeat expands to a repeat length above 200 during maternal transmission, FMR1 becomes methylated and its gene and protein expressions are silenced. Deficiency of the FMR1 protein product FMRP causes fragile X syndrome (FXS), the most commonly inherited form of intellectual disability and autism spectrum disorder. FXS is associated with a wide spectrum of comorbidities, including seizures, sensory hypersensitivity, hyperactivity, impulsivity, anxiety, and impaired learning (1).
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Early Career Investigator Commentary Source Type: research
Abstract Noise hypersensitivity is a poorly understood symptom of Autism Spectrum Disorder (ASD). For some, problem behaviors co-occur with the aversive noise. Limited literature exists on treating noise hypersensitivity; however, noise hypersensitivity may be related to a specific phobia. This case study utilizes modified Cognitive Behavioral Therapy (CBT) to address anxiety, avoidance, and problem behaviors evoked by noise in a teen with ASD and mild Intellectual Disability (ID). Using multi-method assessment and individualized treatment, problem behaviors reduced, and independent coping strategies use occurred....
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research
We examined this association by exploring the gap between cognitive understanding of social behavior and socially adaptive behavior, and its impact on social anxiety symptoms, obsessive-compulsive symptoms, and depressive symptoms, among 53 university students with autism (without intellectual disability). A higher cognition-social adaptation discrepancy was associated with more social anxiety, but this effect was moderated by autistic trait (AT) levels; a greater gap was associated with more avoidance symptoms of social anxiety only among students with high AT. Cognitive flexibility and prosocial behavior may mitigat...
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research
This report describes a young adult female with 3q29 deletion syndrome, autism spectrum disorder, intellectual disability, and anxiety who experienced a sustained, non-medication induced paroxysmal oculogyric dystonia which responded to anticholinergic and antihistaminic medications. This is the first report of paroxysmal oculogyric dystonia associated with this deletion, possibly expanding the phenotypic features of this microdeletion syndrome.
Source: Psychiatric Genetics - Category: Genetics & Stem Cells Tags: Brief Report Source Type: research
ConclusionsWe confirm previous reports showing that individuals with ASD are at high risk for specific anxiety disorders. In particular, high levels of impairments in social motivation and social communication (SRS-2) are indicative of comorbid disorders namely, social anxiety and ASD. Our findings clearly inform diagnostic assessment in ASD and stress the need to take comorbid anxiety disorders into consideration to improve treatment of ASD. To further clarify the impact of social anxiety on social competences and socio-adaptive handicap, longitudinal studies and cluster analysis will be needed in the future.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Do you think maybe you have some of the characteristics of people with autism? Did your score on the Autism Quiz on this site suggest that you might be autistic? Has someone suggested that your behaviors are a little or a lot unusual might be “spectrumy”? Are you worried that having autism can be stigmatizing or that it makes you crazy? Not so fast. Get the facts. People with autism with average to high intelligence but who have difficulty with social skills used to be diagnosed with Asperger syndrome (named after the pediatrician who first characterized the condition in the 1940s). In the latest edition of the...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Aspergers Autism Books Asperger’s Syndrome Autism Spectrum neurotypical Source Type: blogs
Abstract Past research suggests that stress and anxiety are more prevalent in persons with autism as compared to typically developing persons. The Stress Survey Schedule (SSS) was developed in 2001 as a means to measure stressors common to persons with Autism Spectrum Disorder (ASD). The present study compared SSS responses of a sample of students diagnosed with ASD and intellectual disability with a group of typically developing students to explore the divergent validity and internal consistency of this measure, and to assess changes in scores among pre-adolescent and adolescent populations. Results indicated sig...
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research
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