Understanding the magnitude of risk associated with Zika virus infection in pregnancy.
Understanding the magnitude of risk associated with Zika virus infection in pregnancy.
BJOG. 2020 Oct 02;:
Authors: Prabhu M, Riley LE
Abstract
In any pandemic, accurate data regarding adverse perinatal outcomes are critical to clinical management, a current reality with COVID-19. During the Zika virus epidemic, initial data regarding perinatal infection risks were concerning, with adverse pregnancy outcomes reported among 46.7% of affected pregnancies (Brasil et al NEJM 2016; 375: 2321). However, subsequent data demonstrated that the incidence of birth defects attributable to Zika virus was approximately 6%, with most of the risk occurring from first trimester infection (Honein et al JAMA 2017;317: 59). These studies demonstrated that risk estimates are subject to how cohorts are established and how risk is defined.
PMID: 33007152 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Prabhu M, Riley LE Tags: BJOG Source Type: research
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