Global hemostatic status in patients with acute-on-chronic liver failure and septics without underlying liver disease.

CONCLUSIONS: We have found hemostatic changes in ACLF to partially overlap with that of patients with sepsis, and evidence of preserved hemostatic capacity in both patient groups. The notable difference was a profound hyperfibrinogenemia, associated with a thrombogenic clot structure and a marked ex-vivo resistance to fibrinolysis in patients with sepsis.
PMID: 33006808 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - October 1, 2020 Category: Hematology Authors: Lisman T, Arefaine B, Adelmeijer J, Zamalloa A, Corcoran E, Smith JG, Bernal W, Patel VC Tags: J Thromb Haemost Source Type: research