Clinical Features and Correlates of Poor Nighttime Sleepiness in Patients with Parkinson's Disease.

Clinical Features and Correlates of Poor Nighttime Sleepiness in Patients with Parkinson's Disease. Parkinsons Dis. 2020;2020:6378673 Authors: Qin X, Li X, Chen G, Chen X, Shi M, Liu XK, Li ZL, Xin ZE, Gao D Abstract Objective: The present study investigated the clinical features and correlates of poor nighttime sleepiness (PNS) in patients with Parkinson's disease (PD). Methods: One hundred ten patients with PD (divided into PD-PNS group and PD-nPNS group) and forty-seven controls (nPD-PNS group) were enrolled in this study. Demographic information was collected. Patients were assessed according to the unified Parkinson's disease rating scale (UPDRS) and Hoehn-Yahr (H&Y) stage scale. Patients were also evaluated according to the Pittsburgh sleep quality index (PSQI), Epworth sleepiness scale (ESS), rapid eye movement sleep behavior disorder screening questionnaire (RBD-SQ), restless leg syndrome (RLS) diagnosis, Hamilton's depression scale (HAMD), and Hamilton's anxiety scale (HAMA). Results: The prevalence of PNS was 55.45% (61/110) in patients with PD. The PD-PNS group tended to have a longer duration of disease, higher UPDRS-I and UPDRS-III scores, a higher percentage of RLS patients, and higher HAMA and HAMD scores than those of the PD-nPNS group. The PD-PNS group tended to have a higher percentage of RBD and RLS patients and higher HAMA and HAMD scores than those of the nPD-PNS group. Analysis of the PSQI components and PSQI impact factors s...
Source: Parkinsons Disease - Category: Neurology Tags: Parkinsons Dis Source Type: research

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