Celastrol induces ROS-mediated apoptosis via directly targeting peroxiredoxin-2 in gastric cancer cells
Conclusion: Our studies have uncovered a potential Celastrol-interacting protein Prdx2 and a ROS-dependent mechanism of its action. The findings also highlight Prdx2 as a potential target for the treatment of gastric cancer.
Source: Theranostics - Category: Molecular Biology Authors: Xi Chen, Ying Zhao, Wu Luo, Sian Chen, Feng Lin, Xi Zhang, Shijie Fan, Xian Shen, Yi Wang, Guang Liang Tags: Research Paper Source Type: research
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