Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis

Conclusion: We showed that rhein could modulate gut microbiota, which indirectly changed purine metabolism in the intestine and subsequently alleviated colitis. Our study has identified a new approach to the clinical treatment of colitis.

Source: Theranostics - October 3, 2020 Category: Molecular Biology Authors: Jiawei Wu, Zhonghong Wei, Peng Cheng, Cheng Qian, Fangming Xu, Yu Yang, Aiyun Wang, Wenxing Chen, Zhiguang Sun, Yin Lu Tags: Research Paper Source Type: research