circ-PRKCB acts as a ceRNA to regulate p66Shc-mediated oxidative stress in intestinal ischemia/reperfusion

Conclusions: Our findings reveal a crucial role for the circ-PRKCB/miR-339-5p/p66Shc signaling pathway in regulating oxidative stress in the I/R intestine. This pathway may be a potential therapeutic target for intestinal I/R injury.

Source: Theranostics - October 3, 2020 Category: Molecular Biology Authors: Dongcheng Feng, Zhecheng Wang, Yan Zhao, Yang Li, Deshun Liu, Zhao Chen, Shili Ning, Yan Hu, Jihong Yao, Xiaofeng Tian Tags: Research Paper Source Type: research