The ER α -miR-575-p27 feedback loop regulates tamoxifen sensitivity in ER-positive Breast Cancer

Conclusions: Our data reveal the ERα-miR-575-CDKN1B feedback loop in ER+ breast cancer, suggesting that miR-575 can be used as a prognostic biomarker in patients with ER+ breast cancer, as well as a predictor or a promising target for tamoxifen sensitivity.

Source: Theranostics - October 3, 2020 Category: Molecular Biology Authors: Shu-Shu Liu, Yun Li, Hui Zhang, Di Zhang, Xiao-Bei Zhang, Xin Wang, Yue Yu Tags: Research Paper Source Type: research