LncRNA DSCAM-AS1 interacts with YBX1 to promote cancer progression by forming a positive feedback loop that activates FOXA1 transcription network
Conclusion: Our study demonstrated that lncRNA DSCAM-AS1 was transcriptionally activated by super-enhancers driven by FOXA1 and exhibited lineage-specific expression pattern. DSCAM-AS1 can promote cancer progression by interacting with YBX1 and regulating expression of FOXA1 and ERα.
Source: Theranostics - Category: Molecular Biology Authors: Yin Zhang, Yong-Xin Huang, Dan-Lan Wang, Bing Yang, Hai-Yan Yan, Le-Hang Lin, Yun Li, Jie Chen, Li-Min Xie, Yong-Sheng Huang, Jian-You Liao, Kai-Shun Hu, Jie-Hua He, Phei Er Saw, Xiaoding Xu, Dong Yin Tags: Research Paper Source Type: research
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