CSRP2 suppresses colorectal cancer progression via p130Cas/Rac1 axis-meditated ERK, PAK, and HIPPO signaling pathways

Conclusion: Our results suggest that the CSRP2/p130Cas/Rac1 axis can inhibit CRC aggressiveness and metastasis through the Hippo, ERK, and PAK signaling pathways. Therefore, CSRP2 may be a potential therapeutic target for CRC.

Source: Theranostics - October 3, 2020 Category: Molecular Biology Authors: Lixia Chen, Xiaoli Long, Shiyu Duan, Xunhua Liu, Jianxiong Chen, Jiawen Lan, Xuming Liu, Wenqing Huang, Jian Geng, Jun Zhou Tags: Research Paper Source Type: research