Bilateral Corneal Graft Rejection Associated With Pembrolizumab Treatment

Conclusions: We report the first case of corneal graft rejection presumably associated with pembrolizumab immunotherapy. Corneal graft rejection may be successfully managed with corticosteroid therapy. However, constant vigilance and follow-up are advised because of the risk of recurrence in case of continued pembrolizumab treatment. Given the subclinical presentation, baseline ophthalmological screening is advised in all corneal graft patients after initiating immune checkpoint inhibitor therapy.
Source: Cornea - Category: Opthalmology Tags: Case Report Source Type: research