Salivary alpha-1-antitrypsin and macrophage migration inhibitory factor may be potential prognostic biomarkers for oncologic treatment –induced severe oral mucositis

ConclusionsThere is a correlation between the abundance of salivary A1AT and MIF and oncologic treatment –induced OM. The correlation of MIF expression with severe OM appears to be compatible with its physiological pro-inflammatory role. These results open up great possibilities for the use of salivary MIF and A1AT levels as prognostic markers for effective therapeutic interventions, such as photobio modulation therapy, patient-controlled analgesia, or personalized medicaments.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research