A form of secondary ovarian insufficiency (SOI) due to adrenal hypoandrogenism as new infertility diagnosis

ConclusionsThis preliminary report suggests that a surprising portion of young women below age 41, tagged with a diagnosis of POI/POF, due to adrenal hypoandrogenism actually suffer from a form of SOI, at least in some cases amenable to treatment by androgen supplementation. Since true POI/POF usually requires third-party egg donation, correct differentiation between POI and SOI in such women appears of great importance and may warrant a trial stimulation after androgen pre-supplementation for at least 6 weeks.
Source: Endocrine - Category: Endocrinology Source Type: research