Rapid, Fatal Acute Right Ventricular Failure After Locoregional Cytokine Therapy for Uveal Melanoma Liver Metastases.

We describe the case of a 67-year-old man who had metastatic uveal melanoma. Before he underwent liver-directed immunoembolization, he had elevated markers of endothelial dysfunction. He died after the rapid onset of acute right ventricular failure from severe pulmonary hypertension with possible superimposed isolated right ventricular takotsubo cardiomyopathy. In discussing this rare case, we focus on the differential diagnosis.
PMID: 32997782 [PubMed - in process]

Source: Texas Heart Institute Journal - May 31, 2020 Category: Cardiology Authors: Kabadi RA, Shah M, Marhefka GD, George G, Awsare B, Terai M, Sato T Tags: Tex Heart Inst J Source Type: research