Serine-Threonine Kinase Receptor Associate Protein Confers Stemness in Neuroblastoma

Serine-threonine kinase receptor associated protein (STRAP) is a scaffolding protein implicated in tumorigenicity but has not been explored in neuroblastoma. Stem cell-like cancer cells are believed to be responsible for tumor cell self-renewal and cancer recurrence. We sought to determine the role of STRAP in neuroblastoma stem cell-like cancer cells maintenance.

Source: Journal of the American College of Surgeons - September 30, 2020 Category: Surgery Authors: Laura V. Bownes, Adele P. Williams, Raoud Marayati, Colin H. Quinn, Jerry E. Stewart, Juliet Easlick, Joseph T. Whitaker, Pran K. Datta, Elizabeth A. Beierle Tags: Pediatric surgery Source Type: research