Dnmt3b regulates DUX4 expression in a tissue-dependent manner in transgenic D4Z4 mice

Facioscapulohumeral muscular dystrophy (FSHD) is a skeletal muscle disorder that is caused by derepression of the transcription factor DUX4 in skeletal muscle cells. Apart from SMCHD1, DNMT3B was recently iden...

Source: Skeletal Muscle - October 1, 2020 Category: Research Authors: Linde F. Bouwman, Bianca den Hamer, Elwin P. Verveer, Lente J. S. Lerink, Yvonne D. Krom, Silv ère M. van der Maarel and Jessica C. de Greef Tags: Research Source Type: research