Cutaneous Pharmacokinetics of Acyclovir Cream 5% Products: Evaluating Bioequivalence with an In Vitro Permeation Test and an Adaptation of Scaled Average Bioequivalence

ConclusionsThe current study demonstrated that the IVPT method, with an appropriate statistical analysis of the results, is a sensitive and discriminating test that can detect differences in the rate and extent of acyclovir bioavailability in the skin from differently formulated cream products.

http://link.springer.com/10.1007/s11095-020-02821-z

Source: Pharmaceutical Research - September 30, 2020 Category: Drugs & Pharmacology Source Type: research