Hold on Tight: Lagging-Strand DNA Polymerases Synthesize Multiple Okazaki Fragments without Letting Go

Kapadia et  al. (2020) use an innovative single-molecule imaging approach in yeast cells to measure chromatin association of individual replisome subunits, thereby challenging the notion that lagging-strand DNA polymerases frequently dissociate from replisomes during DNA replication in vivo.

Source: Molecular Cell - September 30, 2020 Category: Cytology Authors: Vanessa Kellner, Duncan J. Smith Tags: Preview Source Type: research