A novel LC-MS/MS method for the quantification of ulipristal acetate in human plasma: Application to a pharmacokinetic study in healthy Chinese female subjects.

CONCLUSIONS: The major advantages of the current approach involve one-step precipitation of plasma protein with methanol, high selectivity with a lower limit of quantitation of 0.0500 ng/mL, small plasma volume of 50 µL for processing and a short run time of 4 min per sample, which allow its applicability for a pharmacokinetic study in healthy Chinese subjects. PMID: 32990217 [PubMed - as supplied by publisher]
Source: International Journal of Clinical Pharmacology and Therapeutics - Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research