[Alkaline processing of cantharidin can significanty improve the antitumor activity of cantharidin].
CONCLUSIONS: Processing with sodium hydroxide can significantly improve the antitumor activity of cantharides, which inhibits the proliferation, migration and invasion of A549 cells possibly by down-regulating the expressions of MMP1 and MMP2, promoting apoptosis and increasing the level of IFN-γ.
PMID: 32990225 [PubMed - in process]
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Li X, Li S, Pang J, Huang F, Guo B, Liu H Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research
More News: Cancer | Cancer & Oncology | Lung Cancer | Non-Small Cell Lung Cancer | Sodium | Universities & Medical Training