We Need One Million More Volunteers for the COVID-19 Vaccine Trials

We need one million more citizens to volunteer for the COVID-19 vaccine trials. Almost half a million Americans have signed up to be part of the clinical trials, but in order to complete the study, the COVID-19 Prevention Network—formed by the National Institute of Allergy and Infectious Diseases (NIAID) at the U.S. National Institutes of Health—will need more volunteers, and especially more volunteers from diverse backgrounds. The sooner the clinical trials finish accruing patients the sooner we will have results of the vaccine studies. I am a cancer doctor, but like many doctors and researchers have been called in to assist in any way we can to help the effort to fight COVID-19. We are all seeing too much suffering from this devastating virus. While there are many clinical trials across the country working on treatments for COVID-19 and prevention strategies, few are as important as our national vaccine effort. I teamed with David Ellison, a Hollywood producer, and his amazing team, as well as the incomparable Harrison Ford, to put together a public service announcement to encourage every citizen to consider enrolling in the vaccine trial effort. To aid in this effort, the COVID-19 Prevention Network sent an email out to those that had already volunteered, asking them why they did it. What they received back was overwhelming: an outpouring of inspirational and emotional videos, each giving a personal reason for becoming part of the trials. It’s inspirin...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news

Related Links:

CONCLUSION Pediatric patients with SARS–CoV-2 are at risk for critical illness with severe COVID-19 and MIS-C. Cytokine profiling and examination of peripheral blood smears may distinguish between patients with MIS-C and those with severe COVID-19.FUNDING Financial support for this project was provided by CHOP Frontiers Program Immune Dysregulation Team; National Institute of Allergy and Infectious Diseases; National Cancer Institute; the Leukemia and Lymphoma Society; Cookies for Kids Cancer; Alex’s Lemonade Stand Foundation for Childhood Cancer; Children’s Oncology Group; Stand UP 2 Cancer; Team Connor;...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
The last time most of us gave any thought to antibodies was probably in high school biology, but we’re getting a crash refresher course thanks to COVID-19. They are, after all, the key to our best defenses against SARS-CoV-2, the virus that’s caused the global pandemic. People who have been infected likely rely on antibodies to recover, and antibodies are what vaccines are designed to produce. Or at least that’s what infectious-disease and public-health experts assume for now. Because SARS-CoV-2 is such a new virus, even the world’s best authorities aren’t yet sure what it will take to build p...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
I do not have to stress how important a role food and eating play in our lives. Food is at the base in Maslow’s hierarchy of our needs; it is essential for our survival. It shows perfectly the creativity of humankind: food exists in the richest variety of ingredients, forms, shapes, tastes and colors all over the world from the Greenlandic kiviak (dozens of small birds stuffed into a seal fermented under a rock) through the Liquid Pea Sphere of molecular gastronomy to the tagliatelle with hand-cut meat ragout from the world’s best restaurant, Osteria Francescana. The advent of novel digital health tools will ra...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Food 3d printing genomics Innovation technology GC1 sensors nutrigenomics food sensors Source Type: blogs
Abstract Synthetic or natural derived cell-penetrating peptides (CPPs) are vastly investigated as tools for the intracellular delivery of membrane-impermeable molecules. As viruses are intracellular obligate parasites, viral originated CPPs have been considered as suitable intracellular shuttling vectors for cargo transportation. A total of 310 CPPs were identified in the proteome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Screening the proteome of the cause of COVID-19 reveals that SARS-CoV-2 CPPs (SCV2-CPPs) span the regions involved in replication, protein-nucleotide and protein-protein in...
Source: Infection, Genetics and Evolution - Category: Genetics & Stem Cells Authors: Tags: Infect Genet Evol Source Type: research
In late March, The Washington Post, citing unnamed officials, quoted Dr Anthony S. Fauci ’s response to the demands of modeling the novel coronavirus epidemic: “I’ve looked at all the models. I’ve spent a lot of time on the models. They don’t tell you anything. You can’t really rely upon models.”1 The provocative claim from the Director of the National Institute of Allergy and Infectious Diseases was quickly seized upon by critics of the Coronavirus Task Force’s recommendations. Simulation models, however, are certainly not new and have played a prominent role in epidemiology for many decades.
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Commentary Source Type: research
AbstractObjectivesThe aim of this study is to explore the effectiveness and safety of oral corticosteroids (prednisone) in the treatment of early stage SARS-Cov-2 pneumonia in patients who do not yet meet hospital admission criteria.Trial designRandomized clinical trial, controlled, open, parallel group, to evaluate the effectiveness of steroids in adult patients with confirmed COVID-19, with incipient pulmonary involvement, without hospital admission criteria. Patients will be stratified by the presence or not of radiological data on pneumonia.ParticipantsWe will include patients with early stage SARS-Cov-2 pneumonia who ...
Source: Trials - Category: Research Source Type: clinical trials
(Fred Hutchinson Cancer Research Center) Fred Hutchinson Cancer Research Center has been named the coordinating center for vaccine clinical trials of the COVID-19 Prevention Network (COVPN), funded by the National Institute of Allergy and Infectious Diseases.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Authors: Moelling K, Broecker F Abstract Polluted air poses a significant threat to human health. Exposure to particulate matter (PM) and harmful gases contributes to cardiovascular and respiratory diseases, including allergies and obstructive lung disease. Air pollution may also be linked to cancer and reduced life expectancy. Uptake of PM has been shown to cause pathological changes in the intestinal microbiota in mice and humans. Less is known about the effects of pollution-associated microbiota on human health. Several recent studies described the microbiomes of urban and rural air samples, of the stratosphere ...
Source: Journal of Environmental and Public Health - Category: Environmental Health Tags: J Environ Public Health Source Type: research
The COVID-19 (SARS-CoV-2) pandemic has massively distorted our health care systems and caused catastrophic consequences in our affected communities. The number of victims continues to increase and patients at risk can only be protected to a degree, since the virulent state may be asymptomatic. Risk factors concerning COVID-19-induced morbidity and mortality include advanced age, an impaired immune system, cardiovascular or pulmonary diseases, obesity, diabetes mellitus, and cancer treated with chemotherapy.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
DiscussionWhile awaiting a vaccine, hygiene measures, social distancing and personal protective equipment are the only primary prophylaxis measures against SARS-CoV-2, but they have not been sufficient to protect our healthcare professionals. Some evidence of thein vitro efficacy of hydroxychloroquine against this virus is known, along with some clinical data that would support the study of this drug in the chemoprophylaxis of infection. However, there are still no data from controlled clinical trials in this regard. If our hypothesis is confirmed, hydroxychloroquine can help professionals fight this infection with more gu...
Source: Trials - Category: Research Source Type: clinical trials
More News: Allergy | Allergy & Immunology | Cancer | Cancer & Oncology | Cancer Vaccines | Clinical Trials | COVID-19 | Health | Infectious Diseases | National Institutes of Health (NIH) | Study | Vaccines