Drug overdose mortality is associated with employment status and occupation in the National Longitudinal Mortality Study.

CONCLUSIONS: In a large national cohort followed prospectively for up to 6 years, several employment statuses and occupations are associated with overdose deaths, independent of a range of other factors. Efforts to prevent overdose deaths may benefit from focusing on these high-risk groups. PMID: 32990475 [PubMed - as supplied by publisher]
Source: The American Journal of Drug and Alcohol Abuse - Category: Addiction Authors: Tags: Am J Drug Alcohol Abuse Source Type: research

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We examined the relationship between the metabolic processes of carbon catabolite repression (CCR), nitrogen catabolite repression (NCR) and virulence in a variety of A. fumigatus clinical isolates. A considerable amount of heterogeneity with respect to the degree of CCR and NCR was observed and a positive correlation between NCR and virulence in a neutropenic mouse model of pulmonary aspergillosis (PA) was found. Isolate Afs35 was selected for further analysis and compared to the reference strain A1163, with both strains presenting the same degree of virulence in a neutropenic mouse model of PA. Afs35 metabolome analysis ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Geng-Hong Xia1†, Chao You1,2†, Xu-Xuan Gao1, Xiu-Li Zeng1, Jia-Jia Zhu1, Kai-Yu Xu3, Chu-Hong Tan1, Ruo-Ting Xu1, Qi-Heng Wu1, Hong-Wei Zhou3, Yan He4*‡ and Jia Yin1*‡ 1Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China 2Department of Neurology, The First People's Hospital of Zunyi, Zunyi, China 3State Key Laboratory of Organ Failure Research, Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China 4Microbiome Medicine Center, Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical Univ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
What is Fentanyl? According to the National Institute on Drug Abuse, Fentanyl is a powerful synthetic opioid analgesic that is similar to morphine, but is 50 to 100 times more potent. It is a schedule II prescription drug, and it is typically used to treat patients with severe pain, for side effects surrounding aggressive cancer treatments or to manage pain after major surgery. It can be administered as an injection, a transdermal patch or as a lozenge. Under the medical supervision of a professional, there is little risk for addiction. However, that is not to be overlooked, as any exposure to Fentanyl at all will run the ...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction Recovery Addiction to Pharmaceuticals Detox Resources for Alcohol and Drugs/Opiates Drug Rehab Information Drug Treatment Heroin Medical Substance Abuse Synthetic drug abuse drug abuse epidemic fentanyl opioid Source Type: blogs
Introduction: As the opioid epidemic progresses, a better understanding of those at elevated risk of opioid overdose is needed, particularly for populations whose growing risk may be overlooked. Medicare recipients under age 65 (Medicare-disability beneficiaries [MDBs]) are one such population. We sought to analyze characteristics of opioid-overdose hospitalizations among MDBs and quantify the contribution of this population to opioid-overdose hospitalizations overall. Methods: This retrospective cohort study included patients hospitalized for opioid overdose in the National/Nationwide Inpatient Sample from 1998 to 2013. ...
Source: Journal of the American Board of Family Medicine - Category: Primary Care Authors: Tags: Original Research Source Type: research
Substance use and mental health disorders can result in disability, death, and economic cost. In the United States, rates of death from suicide, drug overdose, and chronic liver disease (a marker for alcohol abuse) have been rising for the past 15 years. G...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
This report briefly describes the indicators and outlines the process used to develop them. PMID: 30075094 [PubMed - as supplied by publisher]
Source: Public Health Reports - Category: International Medicine & Public Health Tags: Public Health Rep Source Type: research
“A crisis is a terrible thing to waste,” is a phrase coined by Stanford economist Paul Romer. Politicians are always in search of new crises to address—new fires to put out—with rapid and decisive action. In their passion to appear heroic to their constituents they often act in haste, not ta king the time to develop a deep and nuanced understanding of the issue at hand, insensitive to the notion that their actions might actually exacerbate the crisis.An example of that lack of understanding was made apparent in a  press release by the office of House Majority Whip Steve Scalise (R-LA) on J...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
UCLAYunfeng LuYunfeng Lu is a professor of chemical and biomolecular engineering in the UCLA Samueli School of Engineerg.  Thiscolumn appeared in the Conversation.“Civilization begins with distillation,” said William Faulkner, a writer and drinker. Although ourthirst for alcohol dates back to the Stone Age, nobody has figured out a good way to deal with the ensuing hangover after getting drunk.As a chemical engineering professor and wine enthusiast, I felt I needed to find a solution. As frivolous as this project may sound, it has serious implications. Between 8 and10 percent of emergency room visits in Am...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Happy New Year from NNLM MAR! We are excited to share information with you about our upcoming projects, classes, and news from around the Middle Atlantic Region. See something of interest? Please share our postings with colleagues in your institutions! Spotlight Welcome, Veronica Leigh Milliner! On January 2, Veronica Leigh Milliner, MLIS, joined NNLM MAR in the newly created position of All of Us Community Engagement Coordinator. Veronica will work within our region and in collaboration with other regional and national All of Us Program partners and the National Network of Libraries of Medicine to develop, pilot, model, a...
Source: NN/LM Middle Atlantic Region Blog - Category: Databases & Libraries Authors: Tags: Weekly Postings Source Type: news
Five years ago today I was at a memorial. Another suicide. Our third doctor in 18 months. Everyone kept whispering, “Why?” I was determined to find out. So I started counting dead doctors. I left the service with a list of 10. Now I have 547. Immediately, I began writing and speaking about suicide. So many distressed doctors (and med students) wrote and phoned me. Soon I was running a de facto international suicide hotline from my home. To date, I’ve spoken to thousands of suicidal doctors; published a book of their suicide letters (free audiobook); attended more funerals; in...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Physician Hospital-Based Medicine Medical school Psychiatry Source Type: blogs
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