Long ‐Term Outcomes of Occipital Nerve Stimulation for New Daily Persistent Headache With Migrainous Features

ConclusionOur experience suggests that ONS is not effective in the treatment of NDPH with migrainous features even in centers with experience in treating chronic migraine with ONS. The difference in response rates of chronic migraine and NDPH with migrainous features supports the concept of a different pathophysiology to the two conditions.
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Case Series Source Type: research

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AbstractIntroductionThe phase 3 PREEMPT trials demonstrated efficacy and tolerability of onabotulinumtoxinA for headache prevention in adults with chronic migraine. OnabotulinumtoxinA significantly reduced headache frequency from baseline vs. placebo at 24  weeks; however, this measure may not fully capture the benefits of treatment. We evaluated the impact of onabotulinumtoxinA on patient-reported outcomes according to headache responder status.MethodsA post hoc analysis pooled 24-week data from the placebo-controlled, randomized, double-blind treatment phases of the PREEMPT trials. Patients were stratified by random...
Source: Pain and Therapy - Category: Anesthesiology Source Type: research
Many people experience pain that lasts more than three months that is neither cancer ‐related nor a headache. The search for a diagnosis and pain relief is often long and can be discouraging.  In this interview, lead author of the recently updated Cochrane ReviewPsychological therapies for the management of chronic pain (excluding headache) in adults  Amanda C de C Williams discusses the findings of this review.Can you tell us about this Cochrane Review and what is new about this update?This review is the third in Cochrane, and the fourth overall, attempting to answer the question of efficacy of psychological i...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news
Kayla Brim laughed when she learned it could take 10 days to get her COVID-19 test results back. “I thought, ‘Okay, well, within 10 days I should be fine,’” she remembers. That was on July 2. More than a month later, Brim is still far from fine. Prior to the pandemic, the 28-year-old from Caldwell, Idaho, juggled homeschooling her two kids with her work as a makeup artist—she was supposed to open her own salon in July. Now, she suffers daily from shortness of breath, exhaustion, excruciating headaches, brain fog, neuropathy, high blood pressure and loss of taste and smell. She feels like &ldqu...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
AbstractPurpose of ReviewChronic low back pain (CLBP) is a major cause of disability in the USA, and it affects approximately 1 in 4 Americans. CLBP patients are commonly referred to or seek out neurosurgical evaluations and opinions for treatment and management.Recent FindingsLiterature shows that only a minority of patients with CLBP may benefit from a surgical procedure. These patients that present to clinic often have been ailing for a considerable amount of time and are eager for effective treatment to alleviate pain. However, determining if a patient with CLBP is a surgical candidate is predicated upon having no succ...
Source: Current Pain and Headache Reports - Category: Neurology Source Type: research
Objective: The aim of this study was to determine if headache profile can predict future disability in patients with tension-type headache (TTH). Materials and Methods: Eighty-three individuals with TTH were recruited. To be included in the study participants needed to fulfill the International Headache Society classification’s criteria for episodic or chronic TTH form and to be at least 18 years old. Baseline clinical outcomes (headache and neck-related disability, kinesiophobia, self-efficacy, and anxiety) and physical outcomes (neck extensors muscles maximum voluntary contraction) were collected for all parti...
Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Original Articles Source Type: research
ConclusionsHeadache pain intensity is as important as frequency when evaluating the clinical response and impact on patient headache-related disability after migraine preventive treatment with OnabotulinumtoxinA.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research
ConclusionsREN used for a series of migraine attacks was effective and well tolerated across attacks. REN may offer a safe and effective non-pharmacological alternative for acute treatment in patients with chronic migraine.Trial RegistrationClinicalTrials.gov identifier, NCT04161807. Retrospectively registered on November 13, 2019.
Source: Pain and Therapy - Category: Anesthesiology Source Type: research
ConclusionTen sessions of fMRI-based rTMS over the left motor cortex may provide long-term pain relief in CM, but further studies are warranted to confirm our preliminary findings.
Source: Neurological Sciences - Category: Neurology Source Type: research
AbstractBackgrounderenumab was safe and effective in clinical trials for the prevention of migraine. However, real-life data are still lacking. Here we report the clinical experience from an Italian real-world setting using erenumab in patients with chronic migraine experiencing previous unsuccessful preventive treatments.MethodsSeventy patients with chronic migraine and failure to ≥4 migraine preventive medication classes initially received monthly erenumab 70 mg s.c. Patients without a clinically meaningful improvement, considered as a >  30% reduction in headache days per month, after &...
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research
CONCLUSIONS: Clinical characteristics, treatment patterns, and health-related quality of life measures are statistically significantly different between insufficient responders and responders to acute treatment in patients with migraine. PMID: 32510611 [PubMed - as supplied by publisher]
Source: Headache - Category: Neurology Authors: Tags: Headache Source Type: research
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