A Randomized Control Trial to Assess Intraoperative and Postoperative Outcomes of Colorado Microdissection Needle Versus Conventional Surgical Knife in Neck Dissection

AbstractAimWe designed a prospective randomized study to assess the outcome of Colorado microdissection needle in comparison with conventional surgical blade for performing neck dissections.Materials and MethodsSixty patients who underwent neck dissection for oral cancers were randomly allocated into two groups. The outcome measurements were in terms of cosmetic outcome of neck scar, intraoperative blood loss, over all operative time, and postoperative neck drain assessment.ResultsThe use of microdissection needle in performing skin incision and neck dissection eliminates the need for local anesthetic with vasoconstrictor along with significant reduction in intraoperative blood loss, postoperative drainage and with acceptable cosmetic outcome. No significant difference was seen in perioperative and postoperative complications between both groups.
Source: Journal of Maxillofacial and Oral Surgery - Category: ENT & OMF Source Type: research

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CONCLUSIONS: Provided that it is administered 60-120 minutes before surgery, sublingual administration of DEX formulated as an oral-mucosal gel may provide a safe and practical means of sedative premedication in adults. PMID: 32889844 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
We report a rare case of lymph node metastasis of papillary thyroid cancer (PTC) incidentally detected in a neck dissection specimen of tongue squamous cell carcinoma (SCC). A 42-year-old Japanese woman was diagnosed with tongue SCC (T1N0M0, Stage I). Partial glossectomy with supraomohyoid neck dissection was performed under general anesthesia, and histopathological examinations revealed primary SCC of the tongue and neck metastasis of PTC in neck dissection specimens. A few months later, total thyroidectomy and left modified radical neck dissection were performed by thyroid surgeons. The histopathological diagnosis was PT...
Source: Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
Sheila N Myatra, Sushan Gupta, Prathamesh S PaiJournal of Anaesthesiology Clinical Pharmacology 2020 36(5):96-104 The severe acute respiratory syndrome corona virus 2(SARS-Cov2) virus replicates in the nasal cavity, nasopharynx, and the oropharynx. During oral surgery, the risk of viral transmission is high during instrumentation in these areas, while performing airway management procedures, the oral surgery itself, and related procedures. During the corona virus disease 2019 (COVID-19) pandemic, patients with an oral pathology usually present for emergency procedures. However, patients with oral cancer, being a semi-emer...
Source: Journal of Anaesthesiology Clinical Pharmacology - Category: Anesthesiology Authors: Source Type: research
AbstractPurpose of ReviewEnhanced recovery after surgery (ERAS) protocols have become common for patients undergoing breast reconstruction, catalyzed by the recent opioid crisis. Here, we review standard ERAS protocol structure and the supporting evidence.Recent FindingsA perioperative multidisciplinary team and multimodal pain management appropriately are the two critical factors for ERAS success. Preoperative counseling, both antibiotic and venous thromboembolic prophylaxis, and multimodal antiemetics are crucial to optimize results. Regional nerve blocks provide an alternative to oral and intravenous opioids. Intraopera...
Source: Current Breast Cancer Reports - Category: Cancer & Oncology Source Type: research
This article reviews specific considerations for biopsy of oral mucosal lesions.
Source: Dermatologic Clinics - Category: Dermatology Authors: Source Type: research
DiscussionWhile awaiting a vaccine, hygiene measures, social distancing and personal protective equipment are the only primary prophylaxis measures against SARS-CoV-2, but they have not been sufficient to protect our healthcare professionals. Some evidence of thein vitro efficacy of hydroxychloroquine against this virus is known, along with some clinical data that would support the study of this drug in the chemoprophylaxis of infection. However, there are still no data from controlled clinical trials in this regard. If our hypothesis is confirmed, hydroxychloroquine can help professionals fight this infection with more gu...
Source: Trials - Category: Research Source Type: clinical trials
The current pandemic is revealing the level of commitment needed from multiple sectors to deliver innovative solutions to tackle severe shortages of personal protective equipment, ventilators, and raw materials. Researchers at the Prakash lab at ...
Source: Medgadget - Category: Medical Devices Authors: Tags: Critical Care Materials Public Health Source Type: blogs
ConclusionsFor oncological patients, our data and experience support the initiation of intrathecal bupivacaine at the following doses: 5 mg/day for catheter tips in the cervical spine, 8 mg/day for catheter tips at T1 –4, and 10 mg/day for catheter tips at T5–8. Given the higher likelihood of adverse effects in catheters at T9‐12 and the lumbar spine, we start at 8 mg/day with close follow‐up of the patient. Initiating these doses allow our patients to safely reach adequate analgesia faster, with a shorte r hospitalization and quicker return to anti‐cancer therapy.
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Clinical Research Source Type: research
ibeault Paul F. Lambert Human head and neck cancers that develop from the squamous cells of the oropharynx (Oropharyngeal Squamous Cell Carcinomas or OPSCC) are commonly associated with the papillomavirus infection. A papillomavirus infection-based mouse model of oropharyngeal tumorigenesis would be valuable for studying the development and treatment of these tumors. We have developed an efficient system using the mouse papillomavirus (MmuPV1) to generate dysplastic oropharyngeal lesions, including tumors, in the soft palate and the base of the tongue of two immune-deficient strains of mice. To maximize efficiency an...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
IJERPH, Vol. 17, Pages 2464: Oncological-Therapy Related Oral Mucositis as an Interdisciplinary Problem—Literature Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17072464 Authors: Kusiak AlicjaJereczek-Fossa Cichońska Alterio Oral mucositis is a toxic side effect of non-surgical cancer treatments: chemotherapy and radiotherapy, which strongly impair quality of life and can not only cause strong pain, but also lead to problems with basic physiological needs as eating and swallowing. Development of oral mucositis is associated with type, dosage, and schedu...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
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