Implications of C1q/TNF-related protein-3 (CTRP-3) and progranulin in patients with acute coronary syndrome and stable angina pectoris
Background:
C1q/TNF-related protein-3 (CTRP-3), an adiponectin paralog, and progranulin were recently identified as novel adipokines which may link obesity with glucose dysregulation and subclinical inflammation. We analyzed the relationship between CTRP-3, progranulin and coronary artery disease (CAD) in Korean men and women.
Methods:
Circulating CTRP-3 and progranulin levels were examined in 362 Korean adults with acute coronary syndrome (ACS, n = 69), stable angina pectoris (SAP, n = 85), and control subjects (n = 208) along with various kinds of cardiometabolic risk factors.
Results:
CTRP-3 concentrations were significantly decreased in patients with ACS or SAP compared to control subjects (P
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Kyung ChoiSoon HwangHo HongHae ChoiHye YooByung-Soo YounSei BaikHong Seo Source Type: research
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