People who regularly use acid reflux drugs are 24% more likely to develop type 2 diabetes

A new study from The Seventh Affiliated Hospital of Sun Yat-sen University found that regular PPI-use was linked to a 24% increased risk of being diagnosed with type 2 diabetes.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Pediatric obesity is a chronic disease which leads to the development of significant health consequences in childhood, and increased risk of morbidity and premature mortality in adulthood. It is now estimated that 4% of children and 9% of adolescents in the United States have severe obesity (BMI ≥ 120% of the 95th percentile for age). (1) Causal factors for obesity include genetics, environment, medications, and behavior.(2) Severe obesity during childhood and adolescence is associated with the development of significant comorbidities such as cardiovascular disease, type 2 diabetes (T2D), obstructive sleep apnea (OSA), ...
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
Obesity is associated with increased intra-abdominal pressure, impaired gastric emptying, and decreased lower esophageal sphincter (LES) pressure, all factors predisposing for gastroesophageal reflux disease (GERD).1 Furthermore, autonomic neuropathy in diabetes may increase the risk of GERD because of abnormal peristalsis and reduced LES pressure. Accordingly, patients with obesity and/or type 2 diabetes have a high prevalence of GERD and esophageal motility disorders. Weight loss reduces acid reflux.
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Research letter Source Type: research
A 74-year-old woman with diet-controlled diabetes mellitus type 2 (hemoglobin A1c level of 5.7%), gastroesophageal reflux disease, hypertension, and hyperlipidemia presented to an outside hospital with a 2-week history of severe fatigue, anorexia, left upper quadrant abdominal pain, and night sweats. She reported no fevers, respiratory or gastrointestinal complaints, sick contacts, recent travel, or illicit drug use. She was retired and lived on a farm with her husband, who was her only sexual partner.
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Residents ’ clinic Source Type: research
AbstractBackgroundAn increase in gastroesophageal reflux disease (GERD) after laparoscopic sleeve gastrectomy (LSG) has been reported, and concomitant hiatal hernia repair (HHR) during LSG is expected to reduce the incidence of post-LSG GERD. In HHR, the hepatic branch of the vagus nerve is anatomically transected. Recent experimental animal models suggest that vagotomy may affect glycemic control and weight loss through a neuroendocrine response.ObjectivesTo examine whether LSG with/without hepatic branch vagotomy (HV) has a clinical impact on glycemic control in patients with obesity and type 2 diabetes mellitus (T2DM). ...
Source: Obesity Surgery - Category: Surgery Source Type: research
  An excerpt from the Wheat Belly Revised &Expanded Edition: Have you ever come home from the grocery store with a fresh container of milk, opened it and immediately realized that it was bad—sour-smelling, curdled, unfit to drink?  Feed it to the cat? Probably not. Lighten your coffee? I don’t think so. Pour it down the sink—yeah, that’s the ticket. Or maybe go back to the store with some of the curdled remains and ask for your money back.  That is what your reaction to conventional dietary advice should be. You should wrinkle your nose at the bad smell that emanates from advice t...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open grain-free wheat belly Source Type: blogs
Conclusion: The anesthetic management of patients presenting with dextrocardia is complex. Preoperative cardiac transthoracic echocardiography can identify cardiac lesions or aberrant anatomy associated with dextrocardia. Proper placement of electrocardiogram electrodes is necessary to avoid false-positive results for perioperative ischemia. Central line access must be adjusted to anatomic variations. Clinicians should have high suspicion for associated pulmonary hypertension and should limit sedatives preoperatively to minimize the cardiovascular effects of hypoxia and/or hypercarbia on the pulmonary vasculature. Finally,...
Source: Ochsner Journal - Category: General Medicine Authors: Source Type: research
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