Peripheral benzodiazepine receptor/18  kDa translocator protein positron emission tomography imaging in a rat model of acute brain injury

ConclusionsPET signal enhancement by PBR/TSPO at the site of brain injury correlated with the activation of microglia and production of inflammatory cytokines. Furthermore, because FEPPA enables the detection of neurotoxic microglia on PET images, we successfully constructed a novel PET detection system that can monitor neurodegenerative diseases.
Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research