Exploring Multiple Sclerosis (MS) and Amyotrophic Lateral Sclerosis (ALS) as neurodegenerative diseases and their treatments: A review.

Exploring Multiple Sclerosis (MS) and Amyotrophic Lateral Sclerosis (ALS) as neurodegenerative diseases and their treatments: A review. Curr Top Med Chem. 2020 Sep 24;: Authors: Deeb O, Nabulsi M Abstract Growing concern about neurodegenerative diseases is becoming a global issue. It is estimated that not only their prevalence will increase but also morbidity and health burden will be really concerning. Scientists, researchers and clinicians share the responsibility of arising the awareness and knowledge about the restricting and handicapping health restrains related to these diseases. Multiple Sclerosis (MS), as one of the prevalent autoimmune diseases, is characterized by abnormal regulation of the immune system that periodically attack parts of the nervous system; brain and spinal cord. Symptoms and impairments include weakness, numbness, visual problems, tingling pain that are quietly variable among patients. Amyotrophic Lateral Sclerosis (ALS) is another neurodegenerative disease that is characterized by degeneration of motor neurons in the brain and spinal cord. Unlike MS, symptoms begin with muscle weakness and progress to affect speech, swallowing and finally breathing. Despite the major differences between MS and ALS, misdiagnosis is still influencing disease prognosis and patient quality of life. Diagnosis depends on obtaining careful history and neurological examination as well as the use of Magnetic resonance imaging (MRI...
Source: Current Topics in Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Top Med Chem Source Type: research