Dengue Viremia Kinetics in Asymptomatic and Symptomatic infection

Dengue is the most important arthropod-borne viral infection worldwide, infecting an estimated 390 million people annually (Bhatt et al., 2013). The incidence of dengue virus (DENV) infection has been rising over the last five decades (Gubler, 2020). The outcome of DENV infection ranges from asymptomatic/inapparent infection, mild self-limited dengue fever (DF) to severe dengue hemorrhagic fever (DHF), with potential development of life-threatening dengue shock syndrome (DSS). The majority of infected individuals, however, have no or insufficient symptoms to result in clinical presentation but could serve as a major reservoir for DENV transmission (Endy, 2002; Endy et al., 11; Grange et al., 2014; ten Bosch et al., 2018).

Source: International Journal of Infectious Diseases - September 25, 2020 Category: Infectious Diseases Authors: Ponpan Matangkasombut, Kajohnpong Manopwisedjaroen, Nada Pitabut, Sasikanya Thaloengsok, Swangjit Suraamornkul, Tawatchai Yingtaweesak, Veasna Duong, Anavaj Sakuntabhai, Richard Paul, Pratap Singhasivanon Source Type: research