Identification of a novel HIV-1 second-generation Circulating Recombinant Forms CRF109_0107 in China

Inter-subtype recombinants play an increasingly central role in the complex and dynamic HIV/AIDS epidemic. At present, 106 Circulate recombinant forms (CRFs) have been identified worldwide. In 2000, CRF07_BC and CRF08_BC were first reported in China, and novel CRFs identified in China has soared since 2013. Inter-subtype recombinant viruses, especially CRF01_AE and CRF07_BC, have become the predominant strains of the HIV-1 epidemic in China.1 The double infection between CRFs established more optimal conditions for the second-generation recombination,2 and many second-generation recombinants were represented by the recombination of CRF01_AE and CRF07_BC fragments, such as CRF79_0107,3 CRF80_0107,4 and CRF102_01075.
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research