Anxiety, depression, and quality of life: a long-term follow-up study of patients with persisting concussion symptoms - Doroszkiewicz C, Gold D, Green RE, Tartaglia MC, Ma J, Tator C.

The objectives of this study were to evaluate the prevalence of clinical symptoms of anxiety and depression and the re...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

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In the last decade there has been an increasing awareness that traumatic brain injury (TBI) and concussion substantially increases risk for developing psychiatric disorders. Even mild TBI increases risk for depression and anxiety disorders such as posttraumatic stress disorder (PTSD) by 2-3 fold, predisposing patients to further functional impairment. This strong epidemiological link supports examination of potential mechanisms driving neuropsychiatric symptom development after TBI. One potential mechanism for increased neuropsychiatric symptoms after TBI is via inflammatory processes, as CNS inflammation can last years after initial injury.
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Review Source Type: research
CONCLUSIONS: Our review highlights that mental health is central to concussion recovery. Assessment, prevention and intervention of mental health status should be integrated into standard follow-up procedures. Further research is needed to clarify the mechanisms underlying observed relationships between mental health, post-concussion symptoms and other psychosocial factors. Results suggest that concussion may both precipitate and exacerbate mental health difficulties, thus impacting delayed recovery and psychosocial outcomes.PMID:33926965 | DOI:10.1136/bjsports-2020-103548
Source: British Journal of Sports Medicine - Category: Sports Medicine Authors: Source Type: research
CONCLUSIONS: Yet, post-concussion syndrome remains a clinical-biological reality. If a diffusion tensor imaging MRI in the acute phase is likely to provide predictive elements for subsequent cognitive dysfunctions, it would appear useful to consider combining biomarkers, and linguistics markers, with the creation of a clinical-radio-bio- neuropsychological score in order to differentiate benign outcomes from neuro- and/or psycho-traumatic disorders. PMID: 33218667 [PubMed - as supplied by publisher]
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
CONCLUSIONS: Concussion in the deployed settings does not occur in isolation, with co-morbid and co-occurring conditions being common. Presence of multiple co-morbidities appears to influence clinical course and overall recovery. Post-traumatic headaches are often phenotypically fully consistent with migraine, and appear related to pre-existing migraine if supported by detailed pre-deployment headache history suggesting same. Careful and comprehensive history taking and evaluation is invaluable in identifying associated conditions including migraine, potentially helping clinicians with more accurate symptom attribution, di...
Source: Headache - Category: Neurology Authors: Tags: Headache Source Type: research
The objective of this study was to compare patients with acute-to-subacute MTBI on post-concussion symptom reporting based on whether they retrospectively endorsed experiencing pre-injury anxiety or depression. Patients with MTBI (n=297; 40.4% men; M=38.2 ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Post-traumatic stress disorder in U.S. military members frequently follows a concussion-like brain injury. Until now, it has been unclear why. A UCLA team of psychologists and neurologists reports that a traumatic brain injury causes changes in a brain region called the amygdala; and the brain processes fear differently after such an injury.“Is one causing the other, and how does that occur?” asked senior author Michael Fanselow, who holds the Staglin Family Chair in Psychology at UCLA and is the director of UCLA’s Staglin Music Festival Center for Brain and Behavioral Health. “We’re learning....
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Conclusions: Taken together, these findings can contribute to the development of enhanced screening tools and supports to help front-line staff identify TBI as a possible contributor to challenges faced by IPV survivors. By this means, women who have experienced IPV will be more likely to break the cycle of abuse and have more positive long-term health outcomes. PMID: 31442093 [PubMed - as supplied by publisher]
Source: Brain Injury - Category: Neurology Tags: Brain Inj Source Type: research
This study aims to explore the acute impact of a mild traumatic brain in...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Zoe M. Tapp, Jonathan P. Godbout and Olga N. Kokiko-Cochran* Department of Neuroscience, Institute for Behavioral Medicine Research, College of Medicine, The Ohio State University, Columbus, OH, United States Each year approximately 1.7 million people sustain a traumatic brain injury (TBI) in the US alone. Associated with these head injuries is a high prevalence of neuropsychiatric symptoms including irritability, depression, and anxiety. Neuroinflammation, due in part to microglia, can worsen or even cause neuropsychiatric disorders after TBI. For example, mounting evidence demonstrates that microglia become &ld...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
UCLA biologists have discovered how head injuries adversely affect individual cells and genes  that can lead to serious brain disorders. The life scientists provide the first cell “atlas” of the hippocampus — the part of the brain that helps regulate learning and memory — when it is affected by traumatic brain injury. The team also proposes gene candidates for treating brain disease s associated with traumatic brain injury, such as Alzheimer’s disease and post-traumatic stress disorder.The researchers studied more than 6,000 cells in 15 hippocampal cell types — the first study of in...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
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