Type 1 diabetes and COVID-19: the “Lockdown effect”
The aim of this study was to evaluate the effect the lockdown imposed during COVID-19 outbreak on the glycemic control of people with Type 1 diabetes (T1D) using Continuous (CGM) or Flash Glucose Monitoring (FGM).
The novel coronavirus disease (COVID-19) has been on the rampage ever since its outbreak in December 2019 in Wuhan, China. To date, the disease has affected over 5.3 million people, inflicting more than 342,000 casualties in over 200 nations worldwide . Although the overall mortality rate of COVID-19 ranges from 1.4 to 7.2% [2,3], patients with underlying co-morbidities like diabetes mellitus (DM) tend to have severe disease, acute respiratory distress syndrome (ARDS) and increased mortality [4,5], People with both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) are at a high risk of poor outcomes with COVID-19 .
At the dawn of 2020, central China faced the outbreak of a highly transmittable, novel strain of the coronavirus, causing severe Illness that was subsequently named SARS-CoV-2 . The coronavirus disease 19 (COVID-19) is characterized by severe acute respiratory syndrome and has a high mortality rate especially among the elderly and people with serious underlying medical conditions irrespectively of age . By the 11th of March and as more than 110 countries have reported numerous cases of COVID-19, WHO declared this outbreak as a pandemic .
The on-going Coronavirus disease (Covid-19), an acute infectious respiratory that could lead to a severe pneumonia till to death, has become the world's leading health headline causing public concerns[1,2]. On January 30, 2020, the World Health Organization (WHO) declared that the new coronavirus outbreak is a public health emergency. Further, on February 22, 2020, the Covid-19 expanded in Italy causing the largest and deadly epidemic in the Country . WHO warned that the most at-risk populations are older and people with pre-existing medical conditions such as high blood pressure, heart disease, lung disease, cancer and diabetes.
The global concern is currently focused on the novel coronavirus, named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was isolated in China in January 2020. This virus is responsible for an outbreak of pneumonia, defined as coronavirus disease 2019 (COVID-19), which appeared in Hubei province (China) at the end of 2019 and later spread worldwide .
NHS ’s first breakdown of underlying health conditions also finds 18% had dementiaCoronavirus – latest updatesSee all our coronavirus coverageOne in four people who havedied in hospital with Covid-19 also had diabetes, the NHS ’s first breakdown of underlying health conditions among the fatalities shows.Of the 22,332 people who died in hospital in England between 31 March and 12 May, 5,873 (26%) suffered from either type 1 or type 2 diabetes, NHS England figures reveal.Continue reading...
ConclusionDespite the limited possibility to exercise and the incumbent psychologic stress, glycaemic control improved in patients with T1D who stopped working during the lockdown, suggesting that slowing down routine daily activities can have beneficial effects on T1D management, at least in the short term.
Preliminary data from China suggest that people with diabetes and other preexisting conditions are more likely to experience serious complications and death from COVID-19 than people without diabetes and other conditions. But COVID-19 and the coronavirus that causes it are new, and researchers are still investigating how they impact immunity. We also know that if a person has diabetes and gets influenza or another infection, they can experience worse health outcomes. The question is why. High blood sugars can interfere with white blood cells’ ability to fight infection. So there’s a possibility that people with...
If any reminder were needed of the power of collaboration in healthcare, it is the global efforts underway to stem the current coronavirus outbreak and to develop treatments for it. Chris Round, Merck ’s Head of International Operations&Global Core Franchises, speaking to eyeforpharma ahead of his eyeforpharma Barcelona Conference 2020 keynote, mentions that Merck is lending its heft to industry efforts to help tackle the emergency. “The industry has shown what it is capable of with HIV and Ebola in the past, so I am hopeful that the industry can pull together very fast.” Partner...