S100A9/CD163 Expression in Circulating Classical Monocytes in Chronic Obstructive Pulmonary Disease.

In conclusion, our results demonstrated increased pro-inflammatory phenotypes in circulating classical monocytes in COPD, providing novel insights to elucidate their roles in the pathogenesis of COPD. Summary at a glance In flow cytometric analyses simultaneously using inflammatory-related S100A9 and anti-inflammatory-related CD163 markers, circulating CD14strongCD16- classical monocytes obtained from patients with COPD showed increased inflammatory phenotypes, as compared to healthy volunteers and smokers with normal lung functions. PMID: 32962431 [PubMed - as supplied by publisher]
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - Category: Respiratory Medicine Tags: COPD Source Type: research