Mesenchymal stem cell therapies for COVID-19: Current status and mechanism of action

Publication date: Available online 23 September 2020Source: Life SciencesAuthor(s): Somaye Sadeghi, Sara Soudi, Abbas Shafiee, Seyed Mahmoud Hashemi
Source: Life Sciences - Category: Biology Source Type: research

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Publication date: Available online 8 October 2020Source: Hematology/Oncology and Stem Cell TherapyAuthor(s): Muhammad Bilal Abid, Saurabh Chhabra, Blake Buchan, Mary Beth Graham, Sameem Abedin, Bicky Thapa, Anita D'Souza, Ben George, Mehdi Hamadani
Source: Hematology Oncology and Stem Cell Therapy - Category: Cancer & Oncology Source Type: research
ConclusionIn this review, we attempted to provide a historical overview of bone marrow history, MSC discovery, characterization, and the first clinical studies conducted.
Source: International Orthopaedics - Category: Orthopaedics Source Type: research
AbstractThe COVID-19 pandemic has placed an unprecedented burden on health care systems and economies around the globe. Clinical evidences demonstrate that SARS-CoV-2 infection produces detrimental levels of pro-inflammatory cytokines and chemokines that can lead to acute respiratory distress syndrome (ARDS) and significant systemic organ damage. Currently, there is no definitive therapy for COVID-19 or associated complications, and with the hope of a safe and effective vaccine in the distant future, the search for an answer is paramount. Mesenchymal stem cells (MSCs) provide a viable option due to their immunomodulatory e...
Source: Human Cell - Category: Cytology Source Type: research
NoveCite, a newly formed subsidiary of Citius Pharmaceuticals, Inc., plans to develop, manufacture and commercialize a unique induced mesenchymal stem cells (NC-iMSCs) Novellus, a Cambridge, Mass-based cell engineering company, has developed patented, ... Biopharmaceuticals, Regenerative Medicine, Licensing Citius Pharmaceuticals, Novellus Therapeutics, mesenchymal stem cells
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conditions:   Covid19;   Prophylaxis Interventions:   Biological: PrimePro;   Other: Placebo Sponsors:   Thomas Advanced Medical LLC;   HeartStem Institute Completed
Source: - Category: Research Source Type: clinical trials
Li L Abstract COVID-19 has unfortunately halted lab work, conferences, and in-person networking, which is especially detrimental to researchers just starting their labs. Through social media and our reviewer networks, we met some early-career stem cell investigators impacted by the closures. Here, they introduce themselves and their research to our readers. PMID: 33007233 [PubMed - as supplied by publisher]
Source: Cell Stem Cell - Category: Stem Cells Authors: Tags: Cell Stem Cell Source Type: research
Source: Infection and Drug Resistance - Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
Abstract The emergence of the global pandemic caused by the novel SARS-CoV-2 virus has motivated scientists to find a definitive treatment or a vaccine against it in the shortest possible time. Current efforts towards this goal remain fruitless without a full understanding of the behavior of the virus and its adaptor proteins. This review provides an overview of the biological properties, functional mechanisms, and molecular components of SARS-CoV-2, along with investigational therapeutic and preventive approaches for this virus. Since the proteolytic cleavage of the S protein is critical for virus penetration int...
Source: International Journal of Biological Macromolecules - Category: Biochemistry Authors: Tags: Int J Biol Macromol Source Type: research
Abstract Until very recently, distance education, including digital science labs, served a rather small portion of postsecondary students in the United States and many other countries. This situation has, however, dramatically changed in 2020 in the wake of the COVID-19 pandemic, which forced colleges to rapidly transit from face-to-face instructions to online classes. Here, we report the development of an interactive simulator that is freely available on the web ( for teaching lab classes in developmental biology. This simulator is based on cellular automata models of neur...
Source: Developmental Biology - Category: Biology Authors: Tags: Dev Biol Source Type: research
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