Response to: Loutradis et al. Longer Dialysis Sessions Improve Cardiac Systolic Function by Reducing Myocardial Stunning

We are grateful for the chance to correspond with Loutradis et al, who reasonably suggest that a decreased volume overload may drive improvement in end-diastolic volume. In response to this idea, we have conducted a further analysis of the ACTIVE Dialysis trial participants to determine if a change in body weight was associated with change in end-diastolic volume, or modified the relationship between this parameter and allocation to extended hours dialysis. As described in detail elsewhere,1,2 95 members of a larger cohort of hemodialysis recipients randomized to extended ( ≥24 hours per week) or standard (12–18 hours per week) hemodialysis for 12 months had cardiac magnetic resonance imaging performed at baseline and study end.

Source: Journal of Cardiac Failure - September 1, 2020 Category: Cardiology Authors: Brendan Smyth, Christopher T Chan, Stuart M Grieve, Rajesh Puranik, Li Zuo, Daqing Hong, Nicholas A Gray, Janak R de Zoysa, Anish Scaria, Martin Gallagher, Vlado Perkovic, Meg Jardine Tags: Letter to the Editor Source Type: research