Kidney Transplant Outcomes in Patients With Adenine Phosphoribosyltransferase Deficiency

Conclusions. Kidney allograft outcomes are good in APRT deficiency patients beginning XOR inhibitor therapy pretransplant. Delay in such treatment is a major cause of premature graft loss in these patients. Increased awareness among clinicians is imperative, promoting early diagnosis of APRT deficiency and pharmacotherapy initiation before kidney transplantation.
Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research