Timing to achieve the highest rate of pCR after preoperative radiochemotherapy in rectal cancer: a pooled analysis of 3085 patients from 7 randomized trials.

CONCLUSION: This pooled analysis suggests that the best time to achieve pCR in LARC is at 10 weeks, considering that the lengthening of SI is not detrimental concerning postoperative complications or survival outcomes. PMID: 32966845 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32966845?dopt=Abstract

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 19, 2020 Category: Radiology Authors: Gambacorta MA, Masciocchi C, Chiloiro G, Meldolesi E, Macchia G, van Soest J, Peters F, Collette L, Gérard JP, Ngan S, Rödel CC, Damiani A, Dekker A, Valentini V Tags: Radiother Oncol Source Type: research