Randomized clinical trial on 7-days-a-week postoperative radiotherapy vs. concurrent postoperative radio-chemotherapy in locally advanced cancer of the oral cavity/oropharynx.

CONCLUSION: Concurrent postoperative RTCT tended to improve locoregional control rate as compared to p-CAIR. This, however, did not transferred into improved overall survival. Postoperative RTCT was associated with a substantial increase in haematological toxicity that negatively affected treatment compliance in this arm.
ADVANCES IN KNOWLEDGE: To our knowledge this is the first trial that compares accelerated radiotherapy and radio-chemotherapy in postoperative treatment for oralcavity/oropharyngeal cancer.
PMID: 32960662 [PubMed - as supplied by publisher]

Source: The British Journal of Radiology - September 21, 2020 Category: Radiology Authors: Wozniak G, Misiołek M, Idasiak A, Dębosz-Suwińska I, Jaworska M, Bal W, Maciejewski B, Miszczyk L, Składowski K, Suwinski R Tags: Br J Radiol Source Type: research