An Osteopathic Modular Approach to Asthma: A Narrative Review.

This article also includes supplemental videos showcasing OMT techniques for asthma management, which were developed by the authors based on recommendations indicated in the literature. PMID: 32961555 [PubMed - as supplied by publisher]
Source: Journal of the American Osteopathic Association - Category: Complementary Medicine Tags: J Am Osteopath Assoc Source Type: research

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National cohort study (n=752,867) found the risk of COVID-19 hospital admission was markedly increased in children with asthma with previous recent hospital admission (HR 6.40; 95% CI 3.27 –12.53) or ≥2 courses of oral corticosteroids (3.53; 1.87-6.67).
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
We report the clinical benefits after switching from omalizumab to mepolizumab in an anti-neutrophil cytoplasmic antibodies-negative eosinophilic granulomatosis with polyangiitis patient on her abdominal and cutaneous manifestations. AbstractEosinophilic granulomatosis with polyangiitis (EGPA) is a systemic vasculitis of small-to-medium-sized vessels. Both eosinophilic infiltration and vasculitis are thought to contribute to multi-organ damage. Some biologics have been used to reduce the required dose of corticosteroids in EGPA, but no single agent can ensure a complete control of this disease. Here, we describe a patient ...
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: CASE REPORT Source Type: research
Am J Physiol Lung Cell Mol Physiol. 2021 Dec 1. doi: 10.1152/ajplung.00315.2021. Online ahead of print.ABSTRACTAsthma and its heterogeneity changes with age. Increased airspace neutrophil numbers contribute to severe steroid-resistant asthma exacerbation in the elderly, which correlates with the changes seen in adult asthmatics. However, whether that resembles the same disease mechanism and pathophysiology in aged and adults is poorly understood. Here, we sought to address the underlying molecular mechanism of steroid-resistant airway inflammation development and response to corticosteroid (Dex) therapy in aged mice. To st...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - Category: Cytology Authors: Source Type: research
CONCLUSIONS: Formoterol and fluticasone polytherapy is frequently chosen by Polish physicians in the treatment of asthma and COPD due to its high efficacy and safety. In accordance with doctors' declaration, in the study group this therapy was characterized by the highest effectiveness and the best tolerance.PMID:34849120 | PMC:PMC8610065 | DOI:10.5114/ada.2020.99945
Source: Advances in Dermatology and Allergology - Category: Dermatology Authors: Source Type: research
From ACAAI 2021, Dr Sandhya Khurana reports on advances in asthma, including novel biologic therapies, burden of corticosteroid use, and racial differences in late effects of COVID-19.Medscape
Source: Medscape Today Headlines - Category: Consumer Health News Tags: None ReCAP Source Type: news
Expert Rev Respir Med. 2021 Nov 30. doi: 10.1080/17476348.2021.2011222. Online ahead of print.ABSTRACTINTRODUCTION: Asthma symptoms can be relieved through a maintenance treatment combining long-acting β2-agonist and inhaled corticosteroids (LABA/ICS). However, for patients with inadequately controlled asthma, the LABA/ICS combination might not be sufficient. Under these conditions, clinical guidelines recommend the administration of inhaled long-acting muscarinic antagonists (LAMA) as an add-on therapy to LABA/ICS to better control asthma and improve lung function. For nearly two decades, the only LAMA to be approved...
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Authors: Source Type: research
Acta Biomed. 2021 Nov 29;92(S7):e2021523. doi: 10.23750/abm.v92iS7.12422.ABSTRACT In the last few years much attention has been focused on research on severe asthma and the role of biologicals in its treatment, also in children. However, mild asthma is way more common in childhood and still causes as many as 30-40% of asthma exacerbations requiring emergency consultation. The management of "intermittent" and "mild persistent" asthma phenotypes is still a matter of debate, even if the role of inhaled corticosteroids, both continuous and intermittent, is a cornerstone in this field. Nevertheless, updates ...
Source: Acta Bio-Medica : Atenei Parmensis - Category: General Medicine Authors: Source Type: research
NPJ Prim Care Respir Med. 2021 Nov 25;31(1):45. doi: 10.1038/s41533-021-00260-w.ABSTRACTIn the beginning of the COVID-19 pandemic, there were major concerns regarding the huge demand for asthma inhalers. Using the primary-care medical records for 614,700 asthma patients between January and June 2020, we found that there was a substantial increase in inhalers solely in March 2020. Patients significantly associated with receiving higher inhaled corticosteroid prescriptions were younger, of higher socioeconomic status, and had milder asthma.PMID:34824265 | DOI:10.1038/s41533-021-00260-w
Source: Primary Care - Category: Primary Care Authors: Source Type: research
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