Spherical depth-sensing nanoindentation of human anterior skull base bones: Establishment of a test protocol.

Spherical depth-sensing nanoindentation of human anterior skull base bones: Establishment of a test protocol. J Mech Behav Biomed Mater. 2020 Oct;110:103954 Authors: Favier V, Gallet P, Ferry O, Jehl JP Abstract The mechanical properties of anterior skull base (ASB) bones are not well understood due to their complex geometry and deep location. However, it is of particular interest for skull base surgeons to appraise the force range they can apply during procedures and know what kind of haptic feedback a simulation device should produce in order to be realistic for trainees. The aim of this study was to establish a measurement protocol to set the level of hydration state, temperature and curve analysis method for spherical depth sensing nanoindentation of ASB bones. A definitive screening design method was used to test the different possible combinations of these factors. Two samples of ASB bones from the heads of two human body donors (two specimens) were selected according to their microstructure as assessed by micro-CT (microtomography): low-porosity (16.87%, sphenoid bone) and high-porosity (79.85%, ethmoid bone). Depth measurement series of 36 nanoindentations (n = 288) were performed on specimen 1 according to the L8 Taguchi orthogonal array to study the effect of temperature (two levels: 20 or 37 °C), hydration state (dry or immerged in physiological saline sodium chloride), and loading curve analysis according to the Hertz...
Source: Journal of the Mechanical Behavior of Biomedical Materials - Category: Materials Science Authors: Tags: J Mech Behav Biomed Mater Source Type: research