Is an Early Form of Breast Cancer More Dangerous Than Thought?

TUESDAY, Sept. 22, 2020 -- Women diagnosed with an early, highly treatable form of breast cancer still face a higher-than-normal risk of eventually dying from the disease, a large new study finds. The study looked at women with ductal carcinoma in...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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AbstractBreast cancer is an invasive tumor that develops in the breast tissue. It is the most common cancer and also the leading cause of cancer mortality among women worldwide. Survival from breast cancer can be increased through advances in screening methods and early diagnosis. Clinical examination, screening using imaging modalities and pathological assessment (biopsy test) are common methods of breast cancer diagnosis. Among these, pathological assessment is a gold standard due to its potential in identifying the cancer type, sub-type and stage. However, current diagnosis using this pathological assessment technique i...
Source: Health and Technology - Category: Information Technology Source Type: research
Ioannis Panagiotis Trontzas, Nikolaos Konstantinos Syrigos, Elias Alexandros KotteasJournal of Cancer Research and Therapeutics 2021 17(4):1112-1114 Human epidermal growth factor receptor 2 (HER-2) is a checkpoint, controlling cell proliferation and differentiation. Trastuzumab, a humanized monoclonal antibody directed against HER-2, is nowadays standard treatment for breast cancer patients whose tumors express HER-2. It is generally well tolerated, with a small number of patients developing mild adverse reactions. Dermatomyositis is a rare adverse event of trastuzumab therapy not well described in the literature. We here...
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSION: In this study of over 450 IDCs, significant statistical associations between tumor grade and receptor status with US imaging morphology were observed and could serve as a surrogate imaging marker for the biological behavior of the tumor.PMID:34513212 | PMC:PMC8422408 | DOI:10.25259/JCIS_60_2021
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSION: BI-RADS findings correspond to similar studies, however, a large number of benign breast disease was diagnosed. This may indicate heightened clinical awareness of breast cancer diagnosis and early detection. A significant percentage of malignancies presented as locally advanced. Except for a lower number of invasive lobular carcinoma, the histological spectrum of malignant disease is similar to comparative studies.PMID:34515426
Source: South African Journal of Surgery - Category: Surgery Authors: Source Type: research
CONCLUSION: In this study of over 450 IDCs, significant statistical associations between tumor grade and receptor status with US imaging morphology were observed and could serve as a surrogate imaging marker for the biological behavior of the tumor.PMID:34513212 | PMC:PMC8422408 | DOI:10.25259/JCIS_60_2021
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSION: BI-RADS findings correspond to similar studies, however, a large number of benign breast disease was diagnosed. This may indicate heightened clinical awareness of breast cancer diagnosis and early detection. A significant percentage of malignancies presented as locally advanced. Except for a lower number of invasive lobular carcinoma, the histological spectrum of malignant disease is similar to comparative studies.PMID:34515426
Source: South African Journal of Surgery - Category: Surgery Authors: Source Type: research
CONCLUSIONS: These results show that APBI is an effective treatment for patients with invasive breast cancer. Expansion of the current eligibility criteria should be considered, though prospective validation is needed. Caution is required when considering APBI for patients with ILC.IMPLICATIONS FOR PRACTICE: In a large retrospective review of 946 patients with early breast cancer treated with partial mastectomy and APBI intracavitary brachytherapy, we demonstrate durable local control. Patients deemed unsuitable or high risk by the American Brachytherapy Society, American Society of Therapeutic Radiation Oncology, and Euro...
Source: The Oncologist - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSION: Screening mammography in women 40-49 performed prior to initiation of ART may identify asymptomatic breast malignancy. In accordance with ACR and SBI guidelines to screen women of this age group, women of this age group should undergo screening mammography prior to ART.PMID:34507268 | DOI:10.1016/j.clinimag.2021.08.028
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research
DiscussionICG administration timing during the angiography phase compared with the EPR phase improved TBR and diagnostic accuracy. Future work will focus on image pattern analysis and adaptation of the camera system to targeting fluorophores specific to breast cancer.
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
ConclusionsBreast cryoablation presents a promising alternative to surgery while offering the benefits of a minimally invasive procedure with minimal risks. Further study within a clinical trial or registry is needed to confirm cryoablation as a viable alternative to surgical excision for appropriately selected low-risk patients.
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
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