Management options for chronic anal fissure: a systematic review of randomised controlled trials

ConclusionThis review of the randomized control data demonstrates that healing was significantly higher amongst those treated with sphincterotomy versus more conservative modalities. Topical nitrites had similar outcomes to botulinum toxin injection but were poorly tolerated in comparison to other treatments. The benefit of sphincterotomy was at a cost of increased complications, notably permanent incontinence.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research